GCP uses an MTU of 1460 because Google's network does weird things. That means the MTU for WireGuard should be 1380. On the GCP box, try adding `MTU=1380` to your config and add this line to PostUp: ` ; iptables -t mangle -A POSTROUTING -p tcp --tcp-flags SYN,RST SYN -j TCPMSS --clamp-mss-to-pmtu`